The level at which people start paying national insurance has risen from £9,880 to £12,570, effective from 6 July.
According to the government, 30 million people across the UK will benefit from this tax cut. It says the increase will lift 2.2 million people out of paying any personal tax.
The threshold change means that 70% of UK workers will pay less national insurance, even after accounting for the Health and Social Care Levy, the government added.
Prime Minister Boris Johnson said: 'We know it's tough for many families across the UK, but we want you to know that this government is on your side.
'Today's tax cut means around 70% of British workers will pay less national insurance - even after accounting for the Health and Social Care Levy that is funding the biggest catch-up programme in NHS history and putting an end to spiralling social care costs.
'So whether you are a receptionist, work in hospitality or are a delivery driver, this tax cut is likely to make you and your family better off.'